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Large-cap pharmaceuticals

The 9 companies in this industry listed on the NYSE and Nasdaq are worth $3.1 tn combined; the largest are Eli Lilly (LLY), Johnson & Johnson (JNJ) and AbbVie (ABBV). For each one: what it does, revenue, margin, free cash flow over the last five years and a score from 0 to 10.

Data as of October 2026

Open contest
9 companies value 3.1 tn revenue 483 bn margin 17.8% free cash flow 119 bn avg. score 5.9
LLY holds 37.6% of the group's value, 1.9x the runner-up
Rank Ticker Company Share Value Revenue Margin FCF 5 years FCF/px Yield What it does · why it is here
1 LLY Eli Lilly
United States · score 6.5
38% 1.2 tn 80 bn 33.5% 28 bn 2.4% 0.5% Drugs for diabetes, obesity, oncology and neurology · Global leader in obesity and diabetes (tirzepatide); world's largest drugmaker by market value
2 JNJ Johnson & Johnson
United States · score 6.3
20% 612 bn 98 bn 21.5% 22 bn 3.6% — Drugs and medical devices, with 138,000 employees · Pharma + medical devices; 60+ years of rising dividends and an AAA rating
3 ABBV AbbVie
United States · score 5.4
16% 500 bn 64 bn 9.8% 18 bn 3.6% 2.4% Biopharma in immunology, oncology and neuroscience · Leader in immunology (Skyrizi, Rinvoq) and aesthetics (Botox)
4 MRK Merck & Co.
United States · score 5.9
11% 354 bn 67 bn 4.8% 16 bn 4.5% 2.3% Medicines and vaccines, with Keytruda · Keytruda, the world's best-selling cancer drug
5 NVO Novo Nordisk
Denmark · score 7.4
6% 172 bn 46 bn 33.1% 8.8 bn 5.2% 4.5% Diabetes and obesity drugs, from Denmark · Lilly's main rival in obesity (semaglutide) and the historic leader in insulin
6 PFE Pfizer
United States · score 5.5
5% 168 bn 64 bn 6.8% 11 bn 6.5% — Drugs and vaccines from its own research · One of the world's largest drugmakers; high yield and expiring patents
7 BMY Bristol-Myers Squibb
United States · score 7.6
4% 120 bn 49 bn 18.9% 11 bn 9.5% 4.2% Biopharma in oncology, hematology and immunology · Strong in oncology and hematology; valuation discount from patent expirations
8 JAZZ Jazz Pharmaceuticals
Ireland · score 6.3
0% 14 bn 4.6 bn 20.4% 1.6 bn 11.8% — Biopharma in sleep, oncology and neuroscience · Niche neuroscience and oncology, with high margins
9 BHC Bausch Health
Canada · score 2.4
0% 2.4 bn 11 bn -10.1% 1.4 bn 60.5% — Specialty pharma: gastroenterology, dermatology and neurology · Dermatology, gastroenterology and a controlling stake in Bausch + Lomb

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What this is. A catalogue, not a guide. Every industry with stocks listed on the NYSE or NASDAQ, the companies contending for its leadership, what each one does according to its own annual report, and the balance sheet it filed with the SEC.

The score runs from 0 to 10 and compares each company with every other one in the almanac on cash generation, profitability, debt, dividends and consistency over the last five years. The higher it is, the better the company fares in that comparison. Curious how much each part weighs? Ask at the bottom of the page.

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